Major Appeals

Decoding pre-eclampsia.

Pre-eclampsia is the most common of the serious complications of pregnancy it can affect the mother and baby. It is caused by a defect in the placenta, which joins the mother and baby and supplies the baby with nutrients and oxygen from the mother’s blood. While we do not know exactly what is the root cause of pre-eclampsia, medical science is expanding our knowledge every day. By definition, pre-eclampsia occurs after 20 weeks (but in very rare cases can occur earlier) and the majority of cases occur in the third trimester.

In its early stages pre-eclampsia is symptomless and is only detectable by regular antenatal checks on the mother’s blood pressure and urine. Pre-eclampsia is known as a multisystem disorder which means it can affect different parts of your body such as your liver, your kidneys, your cardiovascular system or your clotting systems.

Mild pre-eclampsia affects up to 10% of first time pregnancies with severe pre-eclampsia affecting about 1-2 in 100 pregnancies.

Help us to make a huge step forward into decoding the secrets of pre-eclampsia. Our Appeal for 2015/2016 is to raise a stunning £120,000!  This will enable cutting edge research into understanding placental messages from baby to Mum, leading us to the root of the problem.

Professor Redman explains:

“It seems that the placenta, the baby’s life support system from Mum, signals its needs by a constant flow of blood borne messages that are invisible even to the most powerful microscopes. They comprise tiny cell droplets which might be called ‘placental mist’. With new techniques we can analyse placental mist, and begin to decode its messages. Knowing how and why the signals change in pre-eclampsia will move us to the heart of the problem. We are in pole position to do this. The support of the Society will enable quick progress while we gather other grants to keep our momentum going.”

Please support our Appeal and eventually prevent further suffering.